Partial versus radical nephrectomy for renal cell carcinoma

Abstract

Chronic kidney disease risk is increased among patients with renal cell carcinoma, particularly for those with preexisting chronic kidney disease (including proteinuria) but also for those with comorbidities such as diabetes mellitus, hypertension, and obesity. Among those with small renal masses without complex disease, partial nephrectomy should be prioritized given favorable pathologic prognosis and mortality related to cardiovascular disease or chronic kidney disease. Nephrologists should actively participate in a multidisciplinary team to help formulate individualized treatment which will help preserve residual kidney function where possible.