Vernal keratoconjunctivitis: An update

Author:

Ghiglioni Daniele Giovanni1,Zicari Anna Maria2,Parisi Giuseppe Fabio3,Marchese Giuseppe4,Indolfi Cristiana5,Diaferio Lucia6,Brindisi Giulia2,Ciprandi Giorgio7ORCID,Marseglia Gian Luigi89,Miraglia del Giudice Michele5

Affiliation:

1. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano – UOSD Pediatria Alta Intensità di Cura – Ambulatorio Allergologia Pediatrica, Milan, Italy

2. UOS Allergologia Pediatrica, “Sapienza” Università di Roma, Rome, Italy

3. UOC Broncopneumologia Pediatrica, Dipartimento di Medicina Clinica e Sperimentale, Università degli Studi di Catania, Catania, Italy

4. Pediatra di libera scelta, Valcamonica, ATS della Montagna, Brescia, Italy

5. Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, Italy

6. UOC Pediatria Generale e Pronto Soccorso, Azienda Ospedaliero-Universitaria “Consorziale-Policlinico”, Ospedale Pediatrico Giovanni XXIII, Bari, Italy

7. Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy

8. Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

9. Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy

Abstract

Vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) are potentially severe and complex disease in its management among the various allergic eye diseases. In this regard, studies clarified the etiopathogenetic mechanisms. The workup should be multidisciplinary. The treatment includes topical and systemic medications with anti-inflammatory and immunosuppressant activity. However, a definition of nationally- and internationally-shared diagnostic protocols would also be needed and validated access to therapeutic options of proven safety and efficacy to avoid the use of galenic preparations, up to now still essential in the management of moderate-severe VKC. Finally, recognizing VKC and AKC, among rare diseases, at a national and international level would be an essential step to allow the management of VKC with adequate timings and settings within the National Health System.

Publisher

SAGE Publications

Subject

Ophthalmology,General Medicine

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