Increased Salivary Concentration of Human Epidermal Growth Factor in Patients Undergoing CAPD-Reference-Cited by-同舟云学术

Increased Salivary Concentration of Human Epidermal Growth Factor in Patients Undergoing CAPD

Published:1991-07 Issue:3 Volume:11 Page:270-273
ISSN:0896-8608
Container-title:Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
language:en
Short-container-title:Perit Dial Int

Author:

Dagogo-Jack Sam¹,Rodger R. Stuart C.²,Aylor” Pat Kendall I³

Affiliation:

1. Metabolism Division, Washington University School of Medicine, St. Louis, Missouri, U.S.A.

2. Department of Nephrology, Western Infirmary, Glasgow, U.K.

3. Department of Medicine, Roval Victoria Infirmarv, Newcastle Upon Tyne, U.K.

Abstract

Epidermal growth factor (EGF) was measurea In the saliva of 36 patients with chronic renal failure (CRF) and 29 matched control subjects. Salivary EGF in controls was 0.65±0.009 nmol/L compared with 0.99±0.24 nmol/L in nondialyzed CRF patients, 1.15±0.23 in hemodialyzed patients and 1.96±0.25 (p < 0.01, Wilcoxon Rank Sum Test) in CAPO-treated patients. On Sephadex chromatography, the major peak of immunoreactive EGF from patient and control saliva samples coeluted with purified human EGF. We conclude that salivary concentrations of human EGF are significantly elevated in end-stage renal failure, particularly in patients treated by CAPO.

Publisher

SAGE Publications

Subject

Nephrology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/089686089101100314

Reference23 articles.

1. Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal

2. Isolation and structure of urogastrone and its relationship to epidermal growth factor

3. Human epidermal growth factor: isolation and chemical and biological properties.

4. Factors involved in the modulation of cell proliferation in vivo and in vitro: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells

5. Increased thymidine incorporation into fetal rat cartilage in vitro in the presence of human somatomedin, epidermal growth factor and other growth factors

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Comparison of epitheliotrophic factors in autologous serum eyedrops from sera of chronic renal failure patients vs. normal controls;Graefe's Archive for Clinical and Experimental Ophthalmology;2015-05-31

2. Recovery of salivary epidermal growth factor in parotid saliva following parotid sparing radiation therapy: a proof-of-principle study;Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology;2011-01

3. Quantitative Analysis of Age Specific Variation in the Abundance of Human Female Parotid Salivary Proteins;Journal of Proteome Research;2009-10-12

4. The Biology of the Mesothelium during Peritoneal Dialysis;Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis;1995-10