Ultrasonic synthesis, characterization of β-aminoketones by bismuth(III) triflate and determination of antigenotoxic properties-Reference-Cited by-同舟云学术

Ultrasonic synthesis, characterization of β-aminoketones by bismuth(III) triflate and determination of antigenotoxic properties

Published:2013-04-09 Issue:10 Volume:31 Page:911-919
ISSN:0748-2337
Container-title:Toxicology and Industrial Health
language:en
Short-container-title:Toxicol Ind Health

Author:

Ozturkcan S Arda¹,Turhan Kadir¹,Turgut Zuhal¹,Karadayi Mehmet²,Gulluce Medine²

Affiliation:

1. Department of Chemistry, Yildiz Technical University, Istanbul, Turkey

2. Department of Biology, Ataturk University, Erzurum, Turkey

Abstract

Direct-type catalytic Mannich reaction for the synthesis of β-aminoketones from cyclohexanone, substituted aromatic amines and aromatic or hetero-aromatic aldehydes has been applied in water with bismuth triflate under ultrasound. Good yields of the expected β-aminoketones were obtained from available substrates, at room temperature in 1–2 hours. This study was designed to evaluate the mutagenic and antimutagenic potential of synthesized β-aminoketones compounds using Ames/ Salmonella and Escherichia coli WP2 bacterial reverse mutation assay systems.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Toxicology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0748233713484649

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