Effectiveness of bronchial thermoplasty in severe asthma in ‘real life’ patients compared with those recruited to clinical trials in the same centre

Author:

Bicknell Stephen1,Chaudhuri Rekha2,Lee Nicola1,Shepherd Malcolm1,Spears Mark1,Pitman Nick1,Cameron Euan1,Cowan Douglas1,Nixon Julie1,Thompson Joyce1,McSharry Charles3,Thomson Neil C.4

Affiliation:

1. Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK

2. Department of Respiratory Medicine, Gartnavel General Hospital, Glasgow G12 OYN, UK

3. Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK

4. Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK

Abstract

Published information on the effectiveness of bronchial thermoplasty (BT) for severe asthma in ‘real life’ patients is limited. We compared safety and efficacy outcomes 12 months post procedure in 10 clinic patients and 15 patients recruited to clinical trials of BT at the same centre. Baseline asthma severity was greater in the clinic group. Adverse events were similar. Clinical improvements occurred in 50% of the clinic patients compared with 73% of the research patients.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Pulmonary and Respiratory Medicine

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