Intersections of Modifiable Risks: Loneliness is Associated with Poor Subjective Sleep Quality in Older Women at Risk for Alzheimer's Disease

Author:

Danish Madina1ORCID,Dratva Melanie A.2,Lui Kitty K.3,Heyworth Nadine2,Wang Xin2,Malhotra Atul4,Hartman Sheri J.5,Lee Ellen E.6,Sundermann Erin E.26,Banks Sarah J.26

Affiliation:

1. MADURA ADAR Program, University of California, San Diego, La Jolla, CA, USA

2. Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA

3. Joint Doctoral Program in Clinical Psychology, SDSU/UC San Diego, San Diego, CA, USA

4. Department of Medicine, University of California, San Diego, La Jolla, CA, USA

5. Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA

6. Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA

Abstract

We examined the relationship between subjective and objective sleep outcomes and loneliness in older women at risk for Alzheimer's disease (AD). Our sample consisted of 39 participants (aged 65+) with mild cognitive deficits who completed the UCLA Loneliness Scale, the Pittsburgh Sleep Quality Index (PSQI), and an at home sleep test, to determine presence of obstructive sleep apnea. Based on sleep quality scores, individuals categorized as “poor sleepers” had significantly higher loneliness scores than “good sleepers.” However, total loneliness scores did not significantly differ between groups with or without sleep apnea. We found that higher loneliness was significantly associated to lower habitual sleep efficiency and sleep duration and was also influenced by use of sleep medication. Our findings suggest that increased loneliness relates to worse subjective sleep quality, but not to sleep apnea. These findings suggest that combined interventions targeting loneliness and sleep quality may be important for older women.

Funder

California Department of Public Health

National Institute on Aging

Publisher

SAGE Publications

Reference35 articles.

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2. A Systematic Review Assessing Bidirectionality between Sleep Disturbances, Anxiety, and Depression

3. Alzheimer’s Disease Facts and Figures. (2023). Alzheimer’s disease and dementia. Retrieved November 13, 2023, from https://www.alz.org/alzheimers-dementia/facts-figures

4. Alzheimer’s Disease / National Institute of Neurological Disorders and Stroke. (n.d.). Retrieved June 11, 2024, from https://www.ninds.nih.gov/health-information/disorders/alzheimers-disease

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