Efficacy of nature killer cell combination chemotherapy for post-radical gastric cancer metastases: Case report

Author:

Yue Yongting1,Zi Mengmeng2,Feng Jianing1,Wang Wenbang1,Ren Zhaoqi3,Wu Chuntao2,Yang Zhaoyong4ORCID

Affiliation:

1. North China University of Science and Technology, Tangshan, China

2. North China University of Science and Technology Affiliated Hospital, Tangshan, China

3. Department of Transfusion Medicine, PLA Rocket Force Characteristic Medical Center, Beijing, China

4. NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China

Abstract

Nature killer cell therapy has shown strong efficacy in the field of oncology in recent years and has been applied to patients with metastases with the aim of improving the prognosis of advanced gastric cancer. A 59-year-old male with gastric adenocarcinoma with pancreatic metastasis (T4N0M1) who underwent radical surgery for gastric cancer with tumor metastasis was treated with oxaliplatin and tegafur combined with cellular reinfusion in stages. Computed tomograpy scan and serum tumor markers were monitored continuously after the treatment course. After five courses of combined treatment, the patient was in disease control with no significant side effects. At the last follow-up, the alpha fetoprotein had returned to its normal value with a poor display of low-density shadows in the body of the pancreas. Pancreatic cancer is insidious in origin and has a high mortality rate. The report provides clinical evidence for cell therapy of pancreatic metastatic cancer with improved quality of life.

Publisher

SAGE Publications

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