Biosignatures of Health

Abstract

The term health is commonplace in both everyday parlance and professional discourse. Unfortunately, the term has little objective specification, especially in physiologic terms. When critically examined, even time-honored terms such as homeostasis lack specific measurable referents. The last three decades, however, have witnessed an explosion of information from diverse fields regarding the dynamical basis of biology. This brief review explores a few main ideas, which appear to be coming together to provide biosignatures of health.