Proceedings of the 2022 National Toxicology Program Satellite Symposium

Author:

Quist Erin M.1ORCID,Choudhary Shambhunath2ORCID,Lang Richard3,Tokarz Debra A.4ORCID,Hoenerhoff Mark5ORCID,Nagel Jonathan67,Everitt Jeffrey I.8ORCID

Affiliation:

1. Charles River Laboratories, Inc., Durham, North Carolina, USA

2. Pfizer, Inc., Pearl River, New York, USA

3. Wake Forest University, Winston-Salem, North Carolina, USA

4. Experimental Pathology Laboratories, Inc., Durham, North Carolina, USA

5. University of Michigan Medical School, Ann Arbor, Michigan, USA

6. The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

7. North Carolina State University, Raleigh, North Carolina, USA

8. Duke University School of Medicine, Durham, North Carolina, USA

Abstract

The 2022 annual National Toxicology Program Satellite Symposium, entitled “Pathology Potpourri,” was held in Austin, Texas at the Society of Toxicologic Pathology’s 40th annual meeting during a half-day session on Sunday, June 19. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers’ talks along with select images that were used by the audience for voting and discussion. Various lesions and topics covered during the symposium included induced and spontaneous neoplastic and nonneoplastic lesions in the mouse lung, spontaneous lesions in the reproductive tract of a female cynomolgus macaque, induced vascular lesions in a mouse asthma model and interesting case studies in a rhesus macaque, dog and genetically engineered mouse model.

Funder

National Institute of Environmental Health Sciences

Publisher

SAGE Publications

Subject

Cell Biology,Toxicology,Molecular Biology,Pathology and Forensic Medicine

Reference87 articles.

1. Proliferative and Nonproliferative Lesions of the Rat and Mouse Respiratory Tract

2. Cesta MF, Dixon D, Herbert RA, Staska LM. Lung, alveolar/bronchiolar epithelium—hyperplasia. In: Cesta MF, Herbert RA, Brix A, Malarkey DE, Sills RC eds. National Toxicology Program Nonneoplastic Lesion Atlas. 2015. Accessed April 5, 2022. https://ntp.niehs.nih.gov/nnl/respiratory/lung/abephypl/index.htm.

3. Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

4. Endometrial Hyperplasia, Polyps, and Adenomyosis Associated with Unopposed Estrogen in Rhesus Monkeys (Macaca mulatta)

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