A practical review of barriers and challenges to a definitive randomised trial of grafts versus fistula-Reference-Cited by-同舟云学术

A practical review of barriers and challenges to a definitive randomised trial of grafts versus fistula

Published:2024-03-04 Issue: Volume: Page:
ISSN:1129-7298
Container-title:The Journal of Vascular Access
language:en
Short-container-title:J Vasc Access

Author:

Kingsmore David¹²³^ORCID,Edgar Ben¹²^ORCID,Stevenson Karen¹,Greenlaw Nicola⁴,Aitken Emma¹²,Jackson Andrew¹,Thomson Peter⁵^ORCID

Affiliation:

1. Renal Transplant and Vascular Access Surgery, Queen Elizabeth University Hospital, Glasgow, UK

2. School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK

3. Department of Vascular Surgery, Queen Elizabeth University Hospital, Glasgow, UK

4. Glasgow Clinical Trials Unit, Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK

5. Department of Renal Medicine, Queen Elizabeth University Hospital, Glasgow, UK

Abstract

A definitive randomised controlled trial of arteriovenous fistula (AVF) versus arteriovenous grafts (AVG) has been advocated for more than a decade, but as yet, none has been completed. The aim of this article is to summarise the theoretical barriers, review the difficulties in trial design and practicalities that have thus far prevented this from occurring.

Funder

kidney research uk

Publisher

SAGE Publications

Link

http://journals.sagepub.com/doi/pdf/10.1177/11297298241234610

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