Cell-Based and Animal Models for Hepatitis B and C Viruses-Reference-Cited by-同舟云学术

Cell-Based and Animal Models for Hepatitis B and C Viruses

Published:1999-06 Issue:3 Volume:10 Page:99-114
ISSN:2040-2066
Container-title:Antiviral Chemistry and Chemotherapy
language:en
Short-container-title:Antivir Chem Chemother

Author:

Schinazi Raymond F¹²,Ilan Ehud³,Black Paul L⁴,Yao Xuejen¹²,Dagan Shlomo³

Affiliation:

1. Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA

2. Veterans Affairs Medical Center, Decatur, GA 30033, USA

3. XTL Biopharmaceuticals, Kiryat Weizmann, Rehovot 76100, Israel

4. QuadPharma, Decatur, GA 30033, USA

Abstract

Reliable cell-based assays and animal models have been developed for evaluating agents against hepatitis B virus. Although much progress has been made, in vitro and in vivo assays for hepatitis C virus are still on the horizon. Advances towards establishing inexpensive and reliable experimental models have accelerated the development of therapeutic modalities for these life-threatening viral infections. The characterization of well-defined viral targets coupled with improved molecular diagnostic technologies have illuminated this field.

Publisher

SAGE Publications

Link

http://journals.sagepub.com/doi/pdf/10.1177/095632029901000301

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