Opioid Risk Tool, in-hospital opioid exposure, and opioid demand predict pain outcomes following traumatic injury

Author:

Kessler Danielle A1,Webber Heather E2ORCID,de Dios Constanza2ORCID,Yoon Jin H2,Schmitz Joy M2,Lane Scott D2,Harvin John A2,Heads Angela M2,Green Charles E2,Kapoor Shweta3,Stotts Angela L2,Motley Kandice L2,Suchting Robert2

Affiliation:

1. Drexel University College of Medicine at Tower Health, USA

2. University of Texas Health Science Center at Houston, USA

3. Mayo Clinic Alix School of Medicine, Mayo Clinic, USA

Abstract

Prescribed opioids are a mainstay pain treatment after traumatic injury, but a subgroup of patients may be at risk for continued opioid use. We evaluated the predictive utility of a traditional screening tool, the Opioid Risk Tool (ORT), and two other measures: average in-hospital milligram morphine equivalents (MME) per day and an assessment of opioid demand in predicting pain outcomes. Assessments of pain-related outcomes (pain intensity, interference, injury-related stress, and need for additional pain treatment) were administered at 2 weeks and 12 months post-discharge in a sample of 34 patients hospitalized for traumatic injury. Bayesian linear models were used to evaluate changes in responses over time as a function of predictors. High-risk ORT, higher MME per day, and greater opioid demand predicted less change in outcomes over time. This report provides first evidence that malleable factors of opioid and opioid demand have utility in predicting pain outcomes following traumatic injury.

Funder

Louis A. Faillace Endowment

NMOU Core Resource NIH Clinical and Translational Science Award

National Institute on Drug Abuse

UTHealth Learning Healthcare Scholars Program

Publisher

SAGE Publications

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