Isoquinoline Alkaloids from the Leaves of Dehaasia Hainanensis

Abstract

This study was aimed at investigating the alkaloids present in the leaves of Dehaasia hainanensis. Thirteen isoquinolines were isolated and characterized. Of these, four aporphines [(+)-laurolitsine, (+)-corydine, (+)-laurotetanine and (+)-lindcarpine], two morphinans [(-)-sinoacutine and (-)-ocobotrine], four benzylisoquinolines [(+)-reticuline, (+)-roefractine, (+)-reticuline N-oxide, and O-methylarmepavine], and one bisbenzylisoquinoline [(-)-N,N'-dimethyllindoldhamine] are reported for the first time from Dehaasia species. The structures were elucidated by spectral analysis.