Antitobacco Mosaic Virus Activity of a New Eremophilane Glucoside From the Leaves of <i>Nicotiana tabacum</i> L-Reference-Cited by-同舟云学术

Antitobacco Mosaic Virus Activity of a New Eremophilane Glucoside From the Leaves of Nicotiana tabacum L

Published:2022-09 Issue:9 Volume:17 Page:1934578X2211202
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Wang Hui¹,Zhang Li-li¹,Li Yong-sheng¹,Li Shi-tou¹,He Wen-miao¹,Wu Ji-zhong¹,Bi Yi-ming¹,Dai Lu¹,Shen Meng-hao²,Yang Jing²,Tie Jin-xin¹^ORCID

Affiliation:

1. Technology Center, China Tobacco Zhejiang Industrial Co. Ltd, Hangzhou, China

2. College of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou, China

Abstract

A new eremophilane-type sesquiterpene glucoside, 13-hydroxycapsidiol 3- O- β-D-glucoside (1), was isolated from the leaves of Nicotiana tabacum L. The structure of this new metabolite was determined by one-dimensional (1D) and 2D nuclear magnetic resonance (NMR) spectroscopy, high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), and comparison with values reported in the literature. Compound 1 was the second glycosylated eremophilane sesquiterpenoid isolated from plants of the Solanaceae family and exhibited a more potent anti-tobacco mosaic virus (anti-TMV) activity, with an inhibition rate of 39.4% at 20 μM, than the positive control ningnanmycin (34.8%).

Funder

the Foundation of Zhejiang Tobacco Industry Co., Ltd

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X221120216

Reference15 articles.

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