Chemical Constituents of Ligularia Wilsoniana Collected in Chongqing, China

Author:

Okamoto Yasuko1,Taniguchi Mizuho1,Nakashima Katsuyuki1,Gong Xun2,Hanai Ryo3,Kuroda Chiaki4,Tori Motoo1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima, 770-8514 Japan

2. Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, China

3. Department of Life Science and Research Center for Life Science, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan

4. Department of Chemistry and Research Center for Smart Molecules, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan

Abstract

The chemical constituents of Ligularia wilsoniana were studied for the first time, using four samples collected in Chongqing City, China. Two new compounds, 6β-(2′,3′-epoxy-2′-methylpropanoyloxy)-1β,10β-epoxyfuranoeremophilane and 11αH-6β-(2′-hydroxymethylacryloyloxy)-1β,10β;7β,8β-diepoxyeremophilanolide, as well as eight known compounds, were isolated from one of the samples, while three to four known furanoeremophilanes were isolated from the other three samples. No compound was common to the two classes of the samples, demonstrating the presence of at least two chemotypes of this species.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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