Gramine-derived Bromo-alkaloids Activating NF-κB-dependent Transcription from the Marine Hydroid Abietinaria abietina-Reference-Cited by-同舟云学术

Gramine-derived Bromo-alkaloids Activating NF-κB-dependent Transcription from the Marine Hydroid Abietinaria abietina

Published:2016-09 Issue:9 Volume:11 Page:1934578X1601100
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Guzii Alla G.¹,Makarieva Tatyana N.¹,Fedorov Sergey N.¹,Denisenko Vladimir A.¹,Dmitrenok Pavel S.¹,Kuzmich Aleksandra S.¹,Krasokhin Vladimir B.¹,Lee Hyi-Seung²,Lee Yeon-Ju²,Stonik Valentin A.¹

Affiliation:

1. G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Vladivostok-22, Prospect 100-let Vladivostoku 159, Russia

2. Korea Institute of Ocean Science & Technology, Marine Natural Product Chemistry Laboratory, Ansan 426-744, Republic of Korea

Abstract

Two new natural products, 6-bromogramine (1) and bis-6-bromogramine (2) were isolated from the marine hydroid Abietinaria abietina and their structures were established using NMR and MS analysis. Compounds 1 and 2 activate NF-κB-dependent transcriptional activity in JB6 Cl 41 NF-κB cells at 1.6 μM concentrations.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1601100918

Reference19 articles.

1. Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

2. NF-κB as a therapeutic target in neurodegenerative diseases

3. Pyridine Nucleosides Neopetrosides A and B from a Marine Neopetrosia sp. Sponge. Synthesis of Neopetroside A and Its β-Riboside Analogue

4. Abietinarins A and B, cytotoxic metabolites of the marine hydroid Abietinaria sp.

5. The five bromotryptophans

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