Synthesis of Arecatannin A1 from Dimeric Epicatechin Electrophile-Reference-Cited by-同舟云学术

Synthesis of Arecatannin A1 from Dimeric Epicatechin Electrophile

Published:2015-06 Issue:6 Volume:10 Page:1934578X1501000
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Suda Manato¹,Takanashi Kohki¹,Katoh Miyuki¹,Matsumoto Kiriko²,Kawaguchi Koichiro³,Kawahara Sei-Ichi³⁴,Fujii Hiroshi²⁵,Makabe Hidefumi¹⁵

Affiliation:

1. Sciences of Functional Foods, Graduate School of Agriculture, Minami-minowa, Kami-ina, Shinshu University, Nagano, 399–4598, Japan

2. Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399–4598, Japan

3. Interdisciplinary Graduate School of Science and Technology, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399–4598, Japan

4. St. Cousair Co., Ltd., 1260 Imogawa, Kami-minochi, Iizuna, Nagano, 389–1201, Japan

5. Department of Interdisciplinary Genome Sciences and Cell Metabolism, Institute for Biomedical Sciences, Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, Minami-minowa, Kami-ina, Nagano, 399–4598, Japan

Abstract

Synthesis of arrecatannin A1 (1) was accomplished from dimeric epicatechin electrophile, which was prepared by Zn(OTf)2 mediated self-condensation, and monomeric catechin nucleophile. The condensation was successfully worked using Yb(OTf)3 as a Lewis acid in good yield.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1501000642

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