Affiliation:
1. Departamento de Química Orgánica, Instituto de Biotecnología, Facultad de Ciencias, Universidad de Granada, Campus de Fuentenueva, s/n, 18071 Granada, Spain
Abstract
Germacrone (1) forms part of a great number of essential oils, in some of them comprising more than 20% of the total oil. This compound presents a wide range of biological activities (CNS depressant, antiinflammatory, antiulcer, antifeedant, antibacterial, antifungal, antitumor, antitussive, vasodilator, choleretic, hepatoprotector), which are analyzed. The chemical reactivity of germacrone, including cyclization reactions, and complete synthesis are presented.
Subject
Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine
Cited by
3 articles.
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