Chemoenzymatic Total Synthesis of (R)-Dodecanolide and (R)-4-Octanolide

Author:

Sreelakshmi Chittamuru12,Rao Adari Bhaskar1,Narasu Mangamoori Lakshmi2,Reddy Anugu Srinivas1,Reddy Palakondu Janardhan1,SubbaReddy Basi V.3

Affiliation:

1. Medicinal Chemistry and Pharmacology, Hyderabad 500 607, India

2. Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad 500 607, India

3. Natural Product Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 607, India

Abstract

A simple and efficient chemoenzymatic total synthesis of the naturally occurring insect pheromones, (4R)-dodecanolide and (4R)-octanolide is described.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference28 articles.

1. MoriK. (1989) In Techniques in Pheromone Research. HummelHH, MillerT. (Eds). Springer, New York

2. SilversteinRM. (1985) In Semiochemistry, Flavours and Pheromones: Proceedings of the ACS Symposium. AcreeT. (Ed). Walter de Gruyter, Berlin.

3. Recent advances in the chemistry of unsaturated lactones

4. Synthesis of both enantiomers of .gamma.-substituted .alpha.,.beta.-unsaturated .gamma.-lactones

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