Affiliation:
1. Thai Nguyen University-Lao Cai Campus, Lao Cai City, Lao Cai Province, Vietnam
2. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Cau Giay, Hanoi, Vietnam
3. Graduate University of Science and Technology, VAST, Cau Giay, Hanoi, Vietnam
Abstract
Panax pseudoginseng Wall. is famous as a traditional Vietnamese medicinal plant used to promote health and aid in cancer treatment. From the roots of this plant, 1 new (1) and 4 known (2-5) Δ20(22)-dammarane-type triterpenoid glycosides were isolated by various chromatographic methods. Their chemical structures were determined as 3β,6α,12β-trihydroxydammarane-( Z)-20(22),24-diene 6 -O-β-D-glucopyranoside (1), 3β,6α,12β-trihydroxy-dammar-( E)-20(22),25-diene 6 -O-β-D-glucopyranoside (2, ginsenoside Rh4), ginsenoside Rg5 (3), 3β,12β-dihydroxydammarane-( E)-20(22),24-diene 6 -O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside (4), and 3β,12β-dihydroxydammarane-( E)-20(22),24-diene 6 -O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (5). The E/ Z-Δ20(22) configurations in the dammarane compounds were further evidenced by 1D and 2D NMR data.
Funder
Thai Nguyen University of Technology
Subject
Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine