A New Flavone from the Leaves of Astronia formosana-Reference-Cited by-同舟云学术

A New Flavone from the Leaves of Astronia formosana

Published:2018-06 Issue:6 Volume:13 Page:1934578X1801300
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Chen Yu-Chang¹²,Weng Jing-Ru³⁴

Affiliation:

1. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan

2. Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan

3. Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan

4. Doctoral Degree Program in Marine Biotechnology, National Sun Yat-sen University, Kaohsiung 80424, Taiwan

Abstract

A new flavone, 5,4′-dihydroxy-7,3′-dimethoxy-6,8-dimethylflavone (1), together with four known compounds, ursolic acid (2), β-sitosterol-β-D-glucoside (3), β-sitosterol (4) and lupeol (5) were isolated from the methanolic extract of the leaves of Astronia formosana. The structures were elucidated on the basis of physical and spectroscopic data analyses. Compound 1 showed the slight cytotoxicity against MCF-7, SCM-1, and SCC2095 cell lines with IC50 values of 29.3 ± 9.2, 20.5 ± 10.2, and 25.7 ± 2.9 μM, respectively.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801300610

Reference11 articles.

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3. Reagents and Procedures for the Ultraviolet Spectral Analysis of Flavonoids