Re-investigation of the Anthraquinone Pool of Rhamnus spp.: Madagascin from the Fruits of Rhamnus cathartica and R. intermedia

Author:

Epifano Francesco1,Genovese Salvatore1,Kremer Dario2,Randic Marco2,Carlucci Giuseppe1,Locatelli Marcello1

Affiliation:

1. Dipartimento di Scienze del Farmaco, Università “G. D'Annunzio” Chieti-Pescara, Via dei Vestini 31, 66100 Chieti Scalo (CH), Italy

2. Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10000 Zagreb, Croatia

Abstract

As a continuation of our ongoing studies aimed at revealing the presence of oxyprenylated anthraquinones in plants belonging to the genus Rhamnus, in this paper we describe the extraction and HPLC separation of madagascin (3-isopentenyloxyemodin) from the fruits of R. cathartica L. and R. intermedia Steud. & Hochst. The title compound is described herein for the first time as a component of fruit extracts of Rhamnus species.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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