Analytic Review: Interleukin-6 in Surgery, Trauma, and Critical Care: Part I: Basic Science-Reference-Cited by-同舟云学术

Analytic Review: Interleukin-6 in Surgery, Trauma, and Critical Care: Part I: Basic Science

Published:2011-01 Issue:1 Volume:26 Page:3-12
ISSN:0885-0666
Container-title:Journal of Intensive Care Medicine
language:en
Short-container-title:J Intensive Care Med

Author:

Jawa Randeep S.¹,Anillo Sergio²,Huntoon Kristin³,Baumann Heinz³,Kulaylat Mahmoud²

Affiliation:

1. Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA,

2. Department of Surgery, SUNY Buffalo, Buffalo, NY, USA

3. Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY, USA

Abstract

A variety of cytokines play a role in the response to an inflammatory stimulus. The interleukin-6 (IL-6)-type cytokines are released in response to tissue injury or an inflammatory stimulus. They act locally and systemically to generate a variety of physiologic responses, principal among them is the acute phase response. The IL-6 type cytokines demonstrate pleiotropy and redundancy of actions. This is made possible by the distinctive characteristics of the IL-6 receptor complex, which contains an ubiquitous subunit that is shared by most IL-6-type cytokines, as well as a cytokine-specific subunit.

Publisher

SAGE Publications

Subject

Critical Care and Intensive Care Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0885066610395678

Reference93 articles.

1. IL-6 and APPs: anti-inflammatory and immunosuppressive mediators

2. Impaired immune and acute-phase responses in interleukin-6-deficient mice

3. The acute phase response: General aspects

4. Interleukin-6 and the acute phase response

5. C-reactive protein in rheumatology

Cited by 89 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Expression of wound healing markers in gingival crevicular fluid following root-coverage procedures: A systematic review of randomized clinical trials;Archives of Oral Biology;2024-10

2. The Immune System Is a Complex System: Inflammatory Morbidity and Systemic Racism;KZfSS Kölner Zeitschrift für Soziologie und Sozialpsychologie;2024-05-31

3. Assessing the Prognostic Significance of Lactate Levels and Arterial Base Excess in Patients After Pancreatic Surgery: A Retrospective Analysis;Innovative Medicine of Kuban;2024-04-28

4. Light-Enhanced Micropyramidal Sensors for Interleukin-6 Impedance Detection;2024 IEEE Aerospace Conference;2024-03-02

5. Hypocalcaemia upon arrival (HUA) in trauma patients who did and did not receive prehospital blood products: a systematic review and meta-analysis;European Journal of Trauma and Emergency Surgery;2024-02-06