Effect of Propofol Infusion on the Endocrine Response to Cardiac Surgery-Reference-Cited by-同舟云学术

Effect of Propofol Infusion on the Endocrine Response to Cardiac Surgery

Published:1995-10 Issue:5 Volume:23 Page:543-547
ISSN:0310-057X
Container-title:Anaesthesia and Intensive Care
language:en
Short-container-title:Anaesth Intensive Care

Author:

Ng A.¹²,Tan S. S. W.¹²,Lee H. S.¹³,Chew S. L.¹²

Affiliation:

1. Singapore General Hospital and National University of Singapore, Singapore

2. Department of Anaesthesia and Intensive Care, Singapore General Hospital.

3. Department of Pharmacology, National University of Singapore.

Abstract

The effect of propofol infusion on the stress response was studied in patients undergoing coronary artery bypass graft (CABG). Ten patients received propofol infusion during cardiopulmonary bypass (CPB) and ten controls received diazepam. Blood levels of Cortisol, adrenaline and noradrenaline were sampled. There was a significant reduction in all three hormones (P<0.05) in the study group. In addition, the amount of sodium nitroprusside used during CPB was significantly reduced (P<0.05).

Publisher

SAGE Publications

Subject

Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/0310057X9502300502

Reference16 articles.

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4. EFFECT OF HIGH-DOSE FENTANYL ANAESTHESIA ON THE METABOLIC AND ENDOCRINE RESPONSE TO CARDIAC SURGERY

5. Disposition of Propofol Administered as Constant Rate Intravenous Infusions in Humans

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