ICP – could there be a virus in the works?-Reference-Cited by-同舟云学术

ICP – could there be a virus in the works?

Published:2024-06-06 Issue:3 Volume:17 Page:175-178
ISSN:1753-495X
Container-title:Obstetric Medicine
language:en
Short-container-title:Obstet Med

Author:

Giles Sarah K¹,Hague WM “Bill”²^ORCID,Edwards Robert A¹^ORCID

Affiliation:

1. Flinders Accelerator for Microbiome Exploration, Flinders University, Bedford Park, SA, Australia

2. Robinson Research Institute, The University of Adelaide, North Adelaide, SA, Australia

Abstract

Intrahepatic cholestasis of pregnancy (ICP) is the most common liver-specific disorder affecting pregnant women, with an Australian incidence of 0.6% pa and recurring in 70% of those affected. ICP causes mild to severe pruritus, often resulting in considerable skin excoriations, profound sleep disturbances, and severe anxiety, and yet the aetiology and optimal treatment or management of this condition remains unknown. In this review, we consider the role of viruses in causing or exacerbating ICP and discuss viruses that have been most closely implicated in the disease, including the role of Hepatitis B and Hepatitis C viruses in ICP.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Australian Research Council

Publisher

SAGE Publications

Link

https://journals.sagepub.com/doi/pdf/10.1177/1753495X241258385

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