Resistance to Cancer in Amphibians: A Role for Apoptosis?-Reference-Cited by-同舟云学术

Resistance to Cancer in Amphibians: A Role for Apoptosis?

Published:2013-07 Issue:3 Volume:41 Page:231-234
ISSN:0261-1929
Container-title:Alternatives to Laboratory Animals
language:en
Short-container-title:Altern Lab Anim

Author:

Ruben Laurens N.¹,Johnson Rachel O.¹,Clothier Richard H.²,Balls Michael²

Affiliation:

1. Reed College, Portland, Oregon, USA

2. c/o FRAME, Nottingham, UK

Abstract

The rarity of spontaneous cancer in amphibians, and the difficulty of inducing cancer in these lower vertebrates, suggest that they possess an effective system for resistance to the development of cancer. The first part of this narrative presents evidence for cancer resistance in amphibians, and then a variety of studies designed to help understand the physiological basis for this resistance are reviewed. Here, our emphasis is on evidence with regard to the role that apoptosis might play.

Publisher

SAGE Publications

Subject

Medical Laboratory Technology,Toxicology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/026119291304100306

Reference19 articles.

1. “Fertile” Intestine Nuclei

2. The Effect of N-Nitroso-N-Methylurea and N-Dimethylnitrosamine on Cell Mediated and Humoral Immune Responses in Rats and Mice

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