Mediastinal Mature Teratoma With Malignant Carcinomatous Transformation (Somatic-Type Malignancy) With Metastatic Course-Reference-Cited by-同舟云学术

Mediastinal Mature Teratoma With Malignant Carcinomatous Transformation (Somatic-Type Malignancy) With Metastatic Course

Published:2015-06-24 Issue:8 Volume:23 Page:682-684
ISSN:1066-8969
Container-title:International Journal of Surgical Pathology
language:en
Short-container-title:Int J Surg Pathol

Author:

Habougit Cyril¹,Yvorel Violaine¹,Sulaiman Abdulrazzaq¹,Hag Bachir²,Péoc’h Michel¹,Forest Fabien¹

Affiliation:

1. University Hospital of Saint Étienne, Saint Étienne, France

2. Hospital of Pays de Gier, Saint Chamond, France

Abstract

We report the case of a 76-year-old patient presenting with an anterior mediastinal heterogeneous mass. Surgical biopsy revealed a solid and cystic lesion filled with hair. Pathological examination showed an atypical papillary epithelial lining without other germ cell tumor or immature teratoma associated. The final diagnosis was a mature teratoma of the mediastinum with somatic-type malignancy (carcinomatous transformation). After 8-month follow-up, subcutaneous and lymph node metastatic lesions of the carcinomatous component were identified. Subtyping of the malignant component within germ cell tumors is an important challenge for therapeutic options and prognosis.

Publisher

SAGE Publications

Subject

Pathology and Forensic Medicine,Surgery,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1177/1066896915591583

Reference9 articles.

1. Towards the definition of the best management and prognostic factors of teratoma with malignant transformation: a single-institution case series and new proposal

2. Germ Cell Tumors of the Mediastinum

3. Mature Cystic Teratoma With Malignant Transformation to Adenocarcinoma

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Primary germ cell tumours of the mediastinum: A review with emphasis on diagnostic challenges;Histopathology;2023-11-23

2. Metastatic intestinal adenocarcinoma arising within mature teratoma of the mediastinum: report of a surgically-resected case;Chest Disease Reports;2023-10-25

3. Metastatic intestinal adenocarcinoma arising within mature teratoma of the mediastinum: report of a surgically-resected case;Chest Disease Reports;2023-10-25

4. Mediastinal Mature Teratoma with Malignant Transformation into Carcinoid—A Case Report—;Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association);2021

5. Primary Mediastinal Germ Cell Tumors—The University of Western Ontario Experience;Current Oncology;2020-12-08