A review of implantable pulsatile blood pumps: Engineering perspectives

Author:

Wu Tingting1ORCID,Khir Ashraf W2,Kütting Maximilian3,Du Xinli2,Lin Hao1,Zhu Yuxin1,Hsu Po-Lin1

Affiliation:

1. Artificial Organ Technology Laboratory, Biomanufacturing Centre, School of Mechanical and Electrical Engineering, Soochow University, Suzhou, China

2. Brunel Institute for Bioengineering, Brunel University London, Uxbridge, UK

3. R&D, NVT GmbH, Hechingen, Germany

Abstract

It has been reported that long-term use of continuous-flow mechanical circulatory support devices (CF-MCSDs) may induce complications associated with diminished pulsatility. Pulsatile-flow mechanical circulatory support devices (PF-MCSDs) have the potential of overcoming these shortcomings with the advance of technology. In order to promote in-depth understanding of PF-MCSD technology and thus encourage future mechanical circulatory support device innovations, engineering perspectives of PF-MCSD systems, including mechanical designs, drive mechanisms, working principles, and implantation strategies, are reviewed in this article. Some emerging designs of PF-MCSDs are introduced, and possible elements for next-generation PF-MCSDs are identified.

Funder

national natural science foundation of china

national basic research program of china

Young overseas high-level talents introduction plan

Publisher

SAGE Publications

Subject

Biomedical Engineering,Biomaterials,General Medicine,Medicine (miscellaneous),Bioengineering

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