Susac’s syndrome: Leptomeningeal enhancement on 3D FLAIR MRI-Reference-Cited by-同舟云学术

Susac’s syndrome: Leptomeningeal enhancement on 3D FLAIR MRI

Published:2016-04-18 Issue:7 Volume:22 Page:972-974
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Engisch Renate¹,Titelbaum David S²,Chilver-Stainer Lara³,Kellner-Weldon Frauke¹

Affiliation:

1. Institute of Diagnostic and Interventional Neuroradiology, Bern University Hospital, Bern, Switzerland

2. Shields Healthcare, Brockton, MA, USA

3. Department of Neurology, Bern University Hospital, Bern, Switzerland

Abstract

Background: Contrast-enhanced (ce) fluid-attenuated inversion recovery magnetic resonance imaging (FLAIR MRI) has recently been shown to identify leptomeningeal pathology in multiple sclerosis. Objective: To demonstrate leptomeningeal enhancement on three-dimensional (3D) FLAIR in a case of Susac’s syndrome. Methods: Leptomeningeal enhancement was correlated with clinical activity over 20 months and compared to retinal fluorescein angiography. Results: The size, number, and location of leptomeningeal enhancement varied over time and generally correlated with symptom severity. The appearance was remarkably similar to that of retinal vasculopathy. Conclusion: Ce 3D FLAIR may aid in diagnosis and understanding of pathophysiology in Susac’s syndrome and may serve as a biomarker for disease activity.

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458516636836

Reference8 articles.

1. Retinal and Optic Nerve Head Pathology in Susac's Syndrome

2. Brain histopathology in three cases of Susac's syndrome: implications for lesion pathogenesis and treatment: Figure 1

3. Gadolinium-based MRI characterization of leptomeningeal inflammation in multiple sclerosis

4. Comparison of the Added Value of Contrast-Enhanced 3D Fluid-Attenuated Inversion Recovery and Magnetization-Prepared Rapid Acquisition of Gradient Echo Sequences in Relation to Conventional Postcontrast T1-Weighted Images for the Evaluation of Leptomeningeal Diseases at 3T

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Imaging of brain barrier inflammation and brain fluid drainage in human neurological diseases;Cellular and Molecular Life Sciences;2024-01-12

2. Clinical characteristics and treatment approaches in patients with Susac syndrome: a scoping review of cases;Journal of Neurology;2023-09-05

3. Leptomeningeal Interfoliar Enhancement on Vessel Wall MR Imaging as a Unique Radiologic Finding of Susac Syndrome;American Journal of Neuroradiology;2023-02-16

4. Leptomeningeal enhancement under different MS immunotherapies: A monocentric retrospective cohort study of 214 patients;Multiple Sclerosis Journal;2022-09-15

5. Susac’s syndrome – the crucial role of imaging tests for proper diagnosis;Annals of Agricultural and Environmental Medicine;2022-06-02