On-road assessment of fitness-to-drive in persons with MS with cognitive impairment: A prospective study-Reference-Cited by-同舟云学术

On-road assessment of fitness-to-drive in persons with MS with cognitive impairment: A prospective study

Published:2017-08-07 Issue:11 Volume:24 Page:1499-1506
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Morrow Sarah A¹,Classen Sherrilene²,Monahan Miriam³,Danter Tim⁴,Taylor Robert⁵,Krasniuk Sarah⁶,Rosehart Heather¹,He Wenqing⁵

Affiliation:

1. Department of Clinical Neurological Sciences, London Health Sciences Center, Western University, London, ON, Canada

2. School of Occupational Therapy, Western University, London, ON, Canada/Department of Occupational Therapy, University of Florida, Gainesville, FL, USA

3. School of Occupational Therapy, Western University, London, ON, Canada/The Driver Rehabilitation Institute, Santa Rosa, CA, USA

4. School of Occupational Therapy, Western University, London, ON, Canada/All Dominion Driver Training and Traffic Education Centres Limited, Oakville, ON, Canada

5. Department of Statistical and Actuarial Sciences, Western University, London, ON, Canada

6. School of Occupational Therapy, Western University, London, ON, Canada

Abstract

Background: Cognitive impairment is common in multiple sclerosis (MS). In other populations, cognitive impairment is known to affect fitness-to-drive. Few studies have focused on fitness-to-drive in MS and no studies have solely focused on the influence of cognitive impairment. Objective: To assess fitness-to-drive in persons with MS with cognitive impairment and low physical disability. Methods: Persons with MS, aged 18–59 years with EDSS ⩽ 4.0, impaired processing speed, and impairment on at least one measure of memory or executive function, were recruited. Cognition was assessed using the Minimal Assessment of Cognitive Function battery. A formal on-road driving assessment was conducted. Chi-square analysis examined the association between the fitness-to-drive (pass/fail) and the neuropsychological test results (normal/impaired). Bayesian statistics predicting failure of the on-road assessment were calculated. Results: Of 36 subjects, eight (22.2%) were unfit to drive. Only the BVMTR-IR, measuring visual-spatial memory, predicted on-road driving assessment failure ( X2 ( df = 1, N = 36) = 3.956; p = 0.047) with a sensitivity of 100%, but low specificity (35.7%) due to false positives (18/25). Conclusion: In persons with MS and impaired processing speed, impairment on the BVMTR-IR should lead clinicians to address fitness-to-drive.

Funder

National Multiple Sclerosis Society

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458517723991

Reference35 articles.

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