Acute viral hepatitis E presenting with haemolytic anaemia and acute renal failure in a patient with glucose-6-phosphate dehydrogenase deficiency

Author:

Tomar Laxmikant Ramkumarsingh1,Aggarwal Amitesh2,Jain Piyush3,Rajpal Surender4,Agarwal Mukul P5

Affiliation:

1. Senior Resident, Department of Medicine, University College of Medical Sciences and Guru Teg Bahadur Hospital (UCMS & GTBH), University of Delhi, Delhi, India

2. Assistant Professor, Department of Medicine, University College of Medical Sciences and Guru Teg Bahadur Hospital (UCMS & GTBH); University of Delhi, Delhi, India

3. Assistant Professor, Department of Medicine, PGIMER; Physician, RML Hospital, New Delhi, India

4. Specialist, Department of Medicine, University College of Medical Sciences and Guru Teg Bahadur Hospital (UCMS & GTBH), University of Delhi, Delhi, India

5. Professor, Department of Medicine, University College of Medical Sciences and Guru Teg Bahadur Hospital (UCMS & GTBH), University of Delhi, Delhi, India

Abstract

The association of acute hepatitis E viral (HEV) infection with glucose-6-phosphate dehydrogenase (G6PD) deficiency leading to extensive intravascular haemolysis is a very rare clinical entity. Here we discuss such a patient, who presented with acute HEV illness, developed severe intravascular haemolysis and unusually high levels of bilirubin, complicated by acute renal failure (ARF), and was later on found to have a deficiency of G6PD. The patient recovered completely with haemodialysis and supportive management.

Publisher

SAGE Publications

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

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