Neighborhood Socioeconomic Context Predicts Pediatric Asthma Exacerbation

Author:

Kranjac Ashley W.123,Kain Zeev N.245,Ehwerhemuepha Louis6ORCID,Weiss Michael7ORCID,Jenkins Brooke N.248ORCID

Affiliation:

1. Department of Sociology, Chapman University, Orange, CA, USA

2. Center on Stress & Health, School of Medicine, University of California, Irvine, Irvine, CA, USA

3. The Earl Babbie Research Center, Chapman University, Orange, CA, USA

4. Department of Anesthesiology and Perioperative Care, University of California, Irvine, CA, USA

5. Yale Child Study Center, Yale University, New Haven, CT, USA

6. Computational Research, Research Institute, Children’s Health of Orange County, Orange, CA, USA

7. Pediatrics, Children’s Health of Orange County, Orange, CA, USA

8. Department of Psychology, Chapman University, Orange, CA, USA

Abstract

Causes of asthma exacerbation in children have been studied extensively at the individual level, but contributions of neighborhood-level factors are less explored. We test which distinctive residential characteristics produce variation in uncontrolled asthma among pediatric patients. We extracted electronic medical record data from pediatric patients living in Southern California and used multilevel modeling techniques to isolate which neighborhood characteristics drive inequitable asthma control. Above and beyond the individual-level factors known to predict inadequate disease control, neighborhoods with greater concentration of non-Hispanic black residents (odds ratios [OR] = 1.02; 95% confidence interval [CI]: 0.99-1.03; P < .05), higher proportions of female-headed households (OR = 1.01; 95% CI: 0.99-1.01; P < .05), and higher levels of ambient air pollution (OR = 1.05; 95% CI: 1.01-1.10; P < .001) associate with greater odds of asthma exacerbation. The interplay between community characteristics and asthma management during childhood is complex, and place-based initiatives are needed to narrow the gap in asthma exacerbation.

Funder

Kay Family Foundation

Publisher

SAGE Publications

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