Modulation of the Effector Functions of a Human IgG1 through Engineering of Its Hinge Region-Reference-Cited by-同舟云学术

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Modulation of the Effector Functions of a Human IgG1 through Engineering of Its Hinge Region

Published:2006-07-03 Issue:2 Volume:177 Page:1129-1138
ISSN:0022-1767
Container-title:The Journal of Immunology
language:en
Short-container-title:J Immunol

Author:

Dall’Acqua William F.,Cook Kimberly E.,Damschroder Melissa M.,Woods Robert M.,Wu Herren

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference42 articles.

1. Expression of biological effector functions by immunoglobulin G molecules lacking the hinge region.

2. Enhancement of Complement Activation and Cytolysis of Human IgG3 by Deletion of Hinge Exons

3. Activation of complement by an IgG molecule without a genetic hinge

4. Correlation between segmental flexibility and effector function of antibodies

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