Blocking IL-2 Signal In Vivo with an IL-2 Antagonist Reduces Tumor Growth through the Control of Regulatory T Cells
Author:
Publisher
The American Association of Immunologists
Subject
Immunology,Immunology and Allergy
Reference38 articles.
1. Signaling from the IL-2 receptor to the nucleus
2. Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows
3. The main function of IL-2 is to promote the development of T regulatory cells
4. Regulatory T cells exert checks and balances on self tolerance and autoimmunity
5. Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
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