Emergence of traveling waves and their stability in a free boundary model of cell motility

Author:

Rybalko Volodymyr,Berlyand Leonid

Abstract

We consider a 2D free boundary model of cell motility, inspired by the 1D contraction-driven cell motility model due to P. Recho, T. Putelat, and L. Truskinovsky [Phys. Rev. Lett. 111 (2013), p. 108102]. The key ingredients of the model are the Darcy law for overdamped motion of the acto-myosin network, coupled with the advection-diffusion equation for myosin density. These equations are supplemented with the Young-Laplace equation for the pressure and no-flux condition for the myosin density on the boundary, while evolution of the boundary is subject to the acto-myosin flow at the edge.

The focus of the work is on stability analysis of stationary solutions and translationally moving traveling wave solutions. We study stability of radially symmetric stationary solutions and show that at some critical radius a pitchfork bifurcation occurs, resulting in emergence of a family of traveling wave solutions. We perform linear stability analysis of these latter solutions with small velocities and reveal the type of bifurcation (sub- or supercritical). The main result of this work is an explicit asymptotic formula for the stability determining eigenvalue in the limit of small traveling wave velocities.

Funder

National Science Foundation

Publisher

American Mathematical Society (AMS)

Subject

Applied Mathematics,General Mathematics

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Bifurcation of finger-like structures in traveling waves of epithelial tissues spreading;Journal of Mathematical Analysis and Applications;2024-10

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