Isoflavones from Calpurnia aurea subsp. Aurea and their Anticancer Activity
Author:
Publisher
African Journals Online (AJOL)
Subject
Complementary and alternative medicine,Drug Discovery
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Ethnobotanical Study of Mosquito Repellent Plants Used in Seweyna District, Bale Zone, Southeast, Ethiopia;Evidence-Based Complementary and Alternative Medicine;2024-03-15
2. Antidermatophytic quinolizidine alkaloids from Calpurnia aurea subsp. aurea (Aiton) Benth;Fitoterapia;2023-12
3. Antibacterial activity and phytochemical components of leaf extract of Calpurnia aurea;Scientific Reports;2023-06-16
4. Potential of African flora to combat tuberculosis and drug resistance of Mycobacteria: Rationale classification of antimycobacterial agents from a natural source;Advances in Botanical Research;2023
5. From the leaves and bark of the Kenyan medicinal plant Calpurnea aurea subsp. aurea, four previously undescribed quinolizidine alkaloids namely, 2β-Methoxy-13α-o-(2’-pyrrolylcarbonyl) virgiline, 2α-Methoxy-13β-o-(2’-pyrrolylcarbonyl) virgiline, 3α-o-Angelate-2β-hydroxy-13α-o-(2’-pyrrolylcarbonyl) virgiline, -2, 3-Deydro-virgiline were isolated together with four known ones. Structural elucidation of the compounds was based on 1D and 2D NMR spectroscopy and mass spectrometry. Their relative configurations were determined by NOESY correlations and literature. The quinolizidine alkaloids were tested against Trichophyton rubrum, Trichophyton interdigitale, Trichophyton benhamiae, Microsporum canis and Nannizzia gypsea, common causative agents of most of the Tinea infections in human. All the isolated quinolizidine alkaloids exhibited antidermatophytic activity with MIC ranging from 37.5;2023
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