Drugging the undruggable: targeting challenging E3 ligases for personalized medicine
Author:
Affiliation:
1. Facultat de Farmàcia i Ciències de l'Alimentació, Institut de Biomedicina (IBUB), Universitat de Barcelona. Av. Joan XXIII 27–31, 08028 Barcelona, Spain
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.future-science.com/doi/pdf/10.4155/fmc-2017-0009
Reference19 articles.
1. 2015 FDA drug approvals
2. Will the Ubiquitin System Furnish as Many Drug Targets as Protein Kinases?
3. Types of Ubiquitin Ligases
4. Drugging the undruggables: exploring the ubiquitin system for drug development
5. Targeting ubiquitination for cancer therapies
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