Exploring New Imines as Anti-Inflammatory COX and 5-LOX Inhibitors with an Improved Pharmacokinetic Profile-Reference-Cited by-同舟云学术

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Exploring New Imines as Anti-Inflammatory COX and 5-LOX Inhibitors with an Improved Pharmacokinetic Profile

Published:2024-01-31 Issue:4 Volume:16 Page:311-334
ISSN:1756-8919
Container-title:Future Medicinal Chemistry
language:en
Short-container-title:Future Med. Chem.

Author:

Said Mona F¹^ORCID,Moussa Bahia A¹,Mahrouse Marianne A¹^ORCID,Marie Sarah M¹,Mohamed Nada M²

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University,Kasr El-Aini Street, Cairo, PO Box 11562, Egypt

2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Modern University for Technology & Information MTI, Cairo, Egypt

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.4155/fmc-2023-0280

Reference49 articles.

1. Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy? 1 1Abbreviations: NSAIDs, nonsteroidal anti-inflammatory drugs; COX, cyclooxygenase; LT, leukotriene; 5-LOX, 5-lipoxygenase; PG, prostaglandin; DFU, 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsuphonyl)-phenyl-2(5H)-furanone; and DFP, diisopropyl fluorophosphate.

2. Prostanoids in nociception and pain

3. Tolerability of selective cyclooxygenase 2 inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease;Miao X-P;Cochrane Database Syst. Rev.,2014

4. 5-Lipoxygenase Metabolic Contributions to NSAID-Induced Organ Toxicity

5. Medicinal Chemistry Approaches for Multitarget Drugs

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