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Shining a light on Ohno’s dilemma

Published:2024-06-07 Issue: Volume:13 Page:
ISSN:2050-084X
Container-title:eLife
language:en
Short-container-title:

Author:

Tomanek Isabella¹^ORCID

Affiliation:

1. Department of Biology and Department of Biochemistry, University of Oxford

Abstract

Laboratory experiments on a fluorescent protein in E. coli reveal how duplicate genes are rapidly inactivated by mutations during evolution.

Publisher

eLife Sciences Publications, Ltd

Link

https://cdn.elifesciences.org/articles/99318/elife-99318-v1.pdf

Reference11 articles.

1. Gene amplification and adaptive evolution in bacteria;Andersson;Annual Review of Genetics,2009

2. Ohno’s dilemma: evolution of new genes under continuous selection;Bergthorsson;PNAS,2007

3. Shining a light on enzyme promiscuity;Copley;Current Opinion in Structural Biology,2017

4. Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses;Elde;Cell,2012

5. Gene duplication as a mechanism of genomic adaptation to a changing environment;Kondrashov;Proceedings of the Royal Society B,2012

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