Affiliation:
1. D.S.T.S Mandal’s College of Pharmacy, Solapur - 413008, Punyashlok Ahilyadevi Holkar Solapur University, Maharashtra, India.
Abstract
Hyperpigmentation affects people globally with negative psychology impacts. Piper Betle Leaf (PBL) extracts has many benefits including skin lightning which may reduce hyperpigmentation. The objective of this study was to develop an effective skin lightning cream containing PBL with ideal characteristics. A formulation of PBL cream was prepared and physical properties observed. Base and PBL cream had a non-Newtonian property with acceptable color, odor, texture, and showed no phase separation. The developed PBL creams showed significant results in the reduction in melanin content.
Reference10 articles.
1. Khoo, Y.T.; Halim, A.S. Treatment modalities for hyperpigmented skin lesions: A brief overview. J. Surg. Dermatol. 2016, 1, 71–79. [CrossRef]
2. Desai, S.R. Hyperpigmentation Therapy: A Review. J. Clin. Aesthetic Dermatol. 2014, 7, 13–17.
3. Gillbro, J.M.; Olsson, M.J. The melanogenesis and mechanisms of skin-lightening agents-existing and new approaches. Int. J. Cosmet. Sci. 2011, 33, 210–221.
4. Beresniak, A.; Auray, J.-P.; Duru, G.; Aractingi, S.; Krueger, G.G.; Talarico, S.; Adam, A.-S.; Piot, B.; Dupont, D.; De Linares, Y. Impact of pigmentary disorders on quality of life in Japan: Interest of the BeautyQoL instrument. J. Cosmet. Laser Ther. 2015, 17, 313–317.
5. Jennifer, C.; Stephie, C.M.; Abhishri, S.B.; Shalini, B.U. A Review on Skin Whitening Property of Plant Extracts. Int. J. Pharma Bio Sci. 2012, 3, 332–347.