Antioxidant and Anti-inflammatory activity of the Terpenoidal fraction of Ethanolic extract of Byttneria herbacea-Reference-Cited by-同舟云学术

Antioxidant and Anti-inflammatory activity of the Terpenoidal fraction of Ethanolic extract of Byttneria herbacea

Published:2024-04-22 Issue: Volume: Page:1481-1485
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

K. Kar Sanjeeb¹,K. Dixit Prasanna²,S. Mishra Uma³,Chowdhury M. Hossain⁴

Affiliation:

1. Department of Pharmacy, Sarala Birla University, Ranchi, Jharkhand - 835103, India.

2. Department of Zoology, Berhampur University, Berhampur, Odisha - 760007, India.

3. Royal College of Pharmacy and Health Sciences, Berhampur, Odisha - 760002, India.

4. Department of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Kolkata, West Bengal - 700064, India.

Abstract

The goal of this study was to identify the bioactive principle of the plant Byttneria herbacea (Malvaceae) which has a wide range of traditional therapeutic uses.Column chromatography was used to separate the ethanolic extract of aerial parts of the plant with mobile phase Chloroform: Methanol (5:5). The fraction with Rf 0.62 on TLC with mobile phase Toluene:Ethyl acetate (85:15) imparting bluish color under UV 254 nm was giving the test of Terpenoids. The same fraction was assessed for Antioxidant and Anti-inflammatory activity.Antioxidant activity was performed by measuring the decolourizing activity followed by capturing the unpaired electron from the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and compared it with the standard anti-oxidant Gallic acid. To test anti-inflammatory activity in an experimental model of acute inflammation, the carrageenan-induced in rat paw edema method was employed.The antioxidant and the anti-inflammatory activities of the Terpenoid fraction were found to be satisfactory.

Publisher

A and V Publications

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