The effect of Moringa oleifera Leaf Extract Capsules to Anaemia among Post Partum Mothers

Abstract

Factor that affecting maternal mortality is postpartum haemorrhage due to anaemia and it causes uterine subinvolution. Moringa oleifera leaf from South Kalimantan can be used to treat anemia. The aims of this study were phytochemical screening, determining active ingredients, capsule preparation, cytotoxicity evaluation, and clinical study of Moringa leaf extract capsules. Methods of this study were making the extract of Moringa leaf, followed by phytochemical screening using the tube method and measured active ingredients using a UV-Vis spectrophotometer. The next step was making the extract into capsules and it was tested for toxicity using the BSLT method. Moringa leaf extract capsules were also tested among postpartum women with control and experiment group. The experiment group was given Moringa leaf extract capsules and the control group using iron supplements. We measured hemoglobin and hematocrit pre and post intervention. We used SPSS 23rd version. The study showed that Moringa leaf extract contained flavonoid, phenolic, alkaloid, tannin, saponin, steroid and terpenoid compounds. Moringa leaf extract contained a total phenolic was 13.47% and a total flavonoid was 4.17%. The Moringa leaf extract capsule preparation formula produces capsules in good physical properties and not toxic based on BSLT methods. Clinical trials of Moringa leaf extract capsules in postpartum women showed an increase in hemoglobin and hematocrit levels. In addition, statistical analysis showed significant differences between the control group and the experimental group with Moringa leaf extract capsules.