Experience of following up couples affected by hiv and planning pregnancy with use of assisted reproductive technologies in sverdlovsk region-Reference-Cited by-同舟云学术

Experience of following up couples affected by hiv and planning pregnancy with use of assisted reproductive technologies in sverdlovsk region

Published:2023-06-02 Issue:2 Volume:40 Page:22-28
ISSN:2687-1408
Container-title:Perm Medical Journal
language:
Short-container-title:Perm Medical Journal

Author:

Posokhova Larisa A.,Rosyuk Elena A.^ORCID,Shtanova Alexandra A.^ORCID

Abstract

Objective. To analyze the structure of discordant (DC) and concordant (CC) pairs and outcomes of assisted reproductive technologies (ART) without taking into account the correlation of antiretroviral therapy in the Regional Center for AIDS during 2021. Materials and methods. A retrospective analysis of medical records of 210 couples who were consulted at the State Healthcare Institution "RC AIDS" was conducted in order to obtain a conclusion from the medical commission on the possibility of carrying out the ART procedure. The following data were analyzed: channel of infection in men and women, age composition, stage of HIV infection, duration of ART use, ART outcomes. Results. The procedures using ART are carried out in the same percentage as both DC and CC pairs. The outcomes of the ART procedure in PrEP: 2 women (6.9 %) had miscarriage,4 (13.8 %) regression of pregnancy,23 (79.3 %) childbirth; in CC 1 woman (7.7 %) had miscarriage, in the remaining 12 (92.3 %) the procedure was completed with childbirth. Conclusions. As a result of implementing the procedure with ART,35 children were born, not a single case of HIV infection in children was registered.

Publisher

ECO-Vector LLC

Subject

General Medicine

Reference11 articles.

1. UNAIDS. Fact sheet; 2021, available at: https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf.

2. HIV infection in pregnant women: clinical recommendations of the Russian Ministry of Health. Moscow 2021 (in Russian).

3. Medvedeva V.V., Mal'gina G.B. Reproductive issues in HIV-infected couples and the possibility of their correction with the help of assisted reproductive technology (a review). Russian Journal of Human Reproduction 2016; 22 (2): 56–64 (in Russian).

4. Zhukova E.V., Ovodova Yu.V., Ushakova N.V., Tsareva A.S., Pronin A.Yu., Smirnov E.V., Orlova-Morozova E.A., Drobyshevskaya E.V. Experience in monitoring couples planning a pregnancy using assisted reproductive technologies in the Moscow region. Topical issues of HIV infection. Health care for children with HIV infection: Proceedings of the conference. St. Petersburg 2018; 162–164 (in Russian).

5. Reference HIV infection in the Russian Federation as of December 31,2021, available at: https://www.who.int/ru/news-room/fact-sheets/detail/hiv-aids (in Russian).