Enhanced Production of EPA-Derived Anti-Inflammatory Metabolites after Oral Administration of a Novel Self-Emulsifying Highly Purified EPA Ethyl Ester Formulation (MND-2119)-Reference-Cited by-同舟云学术

Enhanced Production of EPA-Derived Anti-Inflammatory Metabolites after Oral Administration of a Novel Self-Emulsifying Highly Purified EPA Ethyl Ester Formulation (MND-2119)

Published:2023-12-01 Issue:12 Volume:30 Page:1927-1949
ISSN:1340-3478
Container-title:Journal of Atherosclerosis and Thrombosis
language:en
Short-container-title:JAT

Author:

Miyoshi Toru¹,Naoe Satoko²,Wakabayashi Hiroyuki²,Yano Takashi²,Mori Takuya³,Kanda Shingo⁴,Arita Makoto⁵,Ito Hiroshi⁶

Affiliation:

1. Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

2. Medical Affairs Department, Mochida Pharmaceutical Co., Ltd

3. Clinical Research Department, Mochida Pharmaceutical Co., Ltd

4. Clinical Development Planning and Management Department, Mochida Pharmaceutical Co., Ltd

5. Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences

6. Department of General Internal Medicine 3, Kawasaki Medical School

Publisher

Japan Atherosclerosis Society

Subject

Biochemistry (medical),Cardiology and Cardiovascular Medicine,Internal Medicine

Link

https://www.jstage.jst.go.jp/article/jat/30/12/30_64135/_pdf

Reference39 articles.

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3. 3) Shojima Y, Ueno Y, Tanaka R, Yamashiro K, Miyamoto N, Hira K, Kurita N, Nakajima S, Urabe T, Hattori N: Eicosapentaenoic-to-Arachidonic Acid Ratio Predicts Mortality and Recurrent Vascular Events in Ischemic Stroke Patients. J Atheroscler Thromb, 2020; 27: 969-977

4. 4) Domei T, Yokoi H, Kuramitsu S, Soga Y, Arita T, Ando K, Shirai S, Kondo K, Sakai K, Goya M, Iwabuchi M, Ueeda M, Nobuyoshi M: Ratio of serum n-3 to n-6 polyunsaturated fatty acids and the incidence of major adverse cardiac events in patients undergoing percutaneous coronary intervention. Circ J, 2012; 76: 423-429

5. 5) Niwa K, Tanaka A, Funakubo H, Otsuka S, Yoshioka N, Kudo N, Tobe A, Sakakibara K, Miki Y, Kataoka T, Furusawa K, Ishii H, Murohara T: The Influence of Eicosapentaenoic Acid to Arachidonic Acid Ratio on Long-term Cardiovascular Events Following Percutaneous Coronary Intervention. Intern Med, 2021; 60: 3865-3871

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