Multi-drug-resistant tuberculosis in COVID-19 pandemic period, Dushanbe

Author:

Tilloeva Z. H.1,Mirzoev A. S.2

Affiliation:

1. State Institution “City Disinfection Station”

2. State Institution “Research Institute of Preventive Medicine of Tajikistan”; State Educational Institution “Institute of Postgraduate Education in Healthcare of the Republic of Tajikistan”

Abstract

Aim. To evaluate the shifts in demographic, clinical, and epidemiological characteristics of patients with multidrugresistant tuberculosis (MDR TB) amidst the COVID-19 pandemic.Materials and Methods. A cross-sectional study was conducted on patients with MDR TB registered in Dushanbe, before (2017-2019) and during the COVID-19 pandemic (2020-2021).Results. The average age of patients prior to the COVID-19 pandemic was 36.5±16.9 years (1.7-79.4), whereas during the COVID-19 period, it was 34.4±17 years (2.9-80.2). The pandemic era witnessed a statistically significant rise in the proportion of workers among MDR TB patients compared to the unemployed (OR = 1.4; 95% CI 1.02-1.91; p = 0.05). Furthermore, an increase was observed in the proportion of patients with lung destruction in both newly diagnosed (OR 3.4; 95% CI 1.99–5.87; p<0.001) and previously treated patients (OR 4.2; 95% CI 1.38–12.99; p =0.002). There was also an increase in extrapulmonary tuberculosis registration (OR=1.7; 95% CI 1.34-2.22; p<0.001), indicating an unfavorable epidemiological situation in terms of MDR-TB. However, there were no statistically significant changes in the registration of concomitant diseases.Conclusion. We recommend the improvement of TB infection prevention and control measures at all levels, as well as the enhancement of early detection of TB and MDR TB patients by primary health care workers.

Publisher

Healthcare of Tajikistan

Reference14 articles.

1. Vasileva I.A. Epidemicheskaya situatsiya po tuberkulezu v gody pandemii COVID-19 – 2020-2021 gg. [Epidemic situation for tuberculosis in the years of the COVID-19 pandemic - 2020-2021.]. Tuberkulez i bolezni legkikh - Tuberculosis and lung diseases, 2022, No. 100 (3), pp. 6-12.

2. Makhmudova P.U. Effektivnost lecheniya bolnykh s lekarstvenno ustoychivymi formami tuberkulyoza lyogkikh v Respublike Tadzhikistan [Effectiveness of Treatment of Patients with DrugResistant Forms of Pulmonary Tuberculosis in the Republic of Tajikistan]. Vestnik Avitsenny - Avicenna Bulletin, 2018, Vol. 20, No. 2-3, pp. 235–239.

3. Ministerstvo zdravookhraneniya i sotsialnoy zashchity naseleniya Respubliki Tadzhikistan. Zdorove naseleniya i deyatelnost uchrezhdeniy zdravookhraneniya v Respublike Tadzhikistan [Ministry of Health and Social Protection of the Republic of Tajikistan. Population Health and Activities of Health Care Institutions in the Republic of Tajikistan]. Dushanbe, 2015-2020.

4. Natsionalnaya programma zashchity naseleniya ot tuberkulyoza v Respublike Tadzhikistan na 20212025 gody ot 27 fevralya 2021 goda, №49 [National program to protect the population from tuberculosis in the Republic of Tajikistan for 2021-2025, February 27, 2021, №49.].

5. Available at: http://www.adlia.tj/show_doc.fwx?Rgn=138961

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3