Treatment of Hirschsprung’s disease in young children

Author:

Mirzoev D. S.1,Ibodov H.2,Yakhshibekova Sh. I.1,Rofiev R. R.3,Kromov T. Sh.4,Latipov Sh. E.3

Affiliation:

1. NEI “Medical and Social Institute of Tajikistan”; SI “Republican Scientific-Clinical Center of Pediatrics and Children’s Surgery”

2. NEI “Medical and Social Institute of Tajikistan”; SEI “Institute of postgraduate training of medical personnel in the field of health care of the Republic of Tajikistan”

3. NEI “Medical and Social Institute of Tajikistan”

4. SEI “Institute of postgraduate training of medical personnel in the field of health care of the Republic of Tajikistan”; SI “Republican Scientific-Clinical Center of Pediatrics and Children’s Surgery”

Abstract

Objective. The objective of this study was to optimize the treatment for Hirschsprung’s disease in young children.Material and methods. A total of 71 children, ranging in age from 3 days to 3 years, were observed. Patients were categorized into three groups based on the surgical procedure performed: 23 underwent transanal endorectal proctoplasty according to De La Torre Mondragon (32.4%), 17 according to the Swenson-like method (23.9%), and 31 according to Soave-Lenyushkin (43.7%).Results and discussion. The results of the maternal examination revealed the presence of cytomegalovirus, herpes virus and toxoplasmosis. The basis for the success of surgical treatment is timely diagnosis. After surgical intervention, histological examination of the surgical material confirmed intestinal agangliosis. Peritoneal-promesenteric proctoplasty according to SoaveLenyushkin in the modification of the clinic, with wedge-shaped excision of the serous-muscular case, is effective in terms of prevention of inter-sheath hematomas and fluid accumulation. The De La Torre-Mondragon and Swenson-like technique of transanal endorectal relegation, without abdominal access with demucosation of the rectum, is considered an effective and minimally invasive access for rectal and rectosigmoidal forms of Hirschsprung’s disease.Conclusions. Transanal endorectal relegation at an early age in children showed rapid recovery of intestinal motility in the postoperative period without skin incision. The results of early surgical intervention contribute to the achievement of good results in the immediate and distant period after the surgical intervention.

Publisher

Healthcare of Tajikistan

Subject

General Medicine

Reference13 articles.

1. Akhparov N.N. Uluchshenie rezultatov khirurgicheskogo lecheniya bolezni Girshprunga u detey [Improving the results of surgical treatment of Hirschsprung’s disease in children]. Pediatriya i detskaya khirurgiya – Pediatrics and pediatric surgery, 2019, No. 2, pp. 42.

2. Goldshteyn A.M. Klinicheskie aspekty neyrointestinalnykh zabolevaniy: patofiziologiya, diagnostika i lechenie [Clinical aspects of neurointestinal diseases: pathophysiology, diagnosis and treatment]. Biologiya razvitiya – Biology of development, 2016, No. 417, pp. 217–28.

3. Dronov A.F., Smirnov A.N., Kholostova V.V. Operatsiya Soave pri bolezni Girshprunga u detey – 50 letniy opyt primeneniya [Soave surgery for Hirschsprung’s disease in children – 50 years of experience]. Detskaya khirurgiya im. Yu.F. Isakova – Pediatric Surgery. Journal named after Yu.F. Isakov, 2016, No. 6, pp. 303–309

4. Dzhenalaev B.K. Rezultaty khirurgicheskogo lecheniya bolezni Girshprunga u detey: Retrospektivnoe issledovanie [Results of surgical treatment of Hirschsprung’s disease in children: A retrospective study]. West Kazakhstan Medical Journal, 2021, No. 1, pp. 11-17.

5. Razumovskiy A.Yu. Bolezn Girshprunga u detey [Hirschsprung’s disease in children]. Moscow, GEOTARMedia Publ., 2019. 368 p.

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