Effectiveness of antianemic therapy for patients with severe iron deficiency anemia-Reference-Cited by-同舟云学术

Effectiveness of antianemic therapy for patients with severe iron deficiency anemia

Published:2024-02-26 Issue:4 Volume: Page:109-116
ISSN:0514-2415
Container-title:Health care of Tajikistan
language:
Short-container-title:jour

Author:

Emomzoda I. Kh.¹,Odinaev Sh. F.²,Rajabzoda M. E.¹,Tursunov R. A.³

Affiliation:

1. Republican Clinical Center of Cardiology

2. Avicenna Tajik State Medical University

3. Tajik National University, Faculty of Medicine

Abstract

Aim. To assess the effectiveness of antianemic therapy in patients with severe iron deficiency anemia.Material and Methods. For inpatient treatment, 30 patients with severe iron deficiency anemia, who exhibited significant cardiovascular system disturbances in the form of developed cardiomyopathy of anemic origin, were selected.Results and discussion. Therefore, the therapy conducted on average contributes to an increase in hemoglobin level by 5.0-6.0 g/l, serum iron by 1.25 µmol/l, and erythrocytes up to 4.0±0.03. In addition to the pronounced clinical effect, patients showed an increase in hemoglobin levels from 75.0±4.5 g/l to 95.0±5.0 g/l. The content of total lipids did not change significantly.Conclusion. The treatment course conducted in patients with severe forms of anemia was found to contribute to an increase in the number of erythrocytes, and levels of hemoglobin, hematocrit, serum iron, and ferritin. This suggests its effectiveness and safety as a treatment method for patients with iron deficiency anemia in the context of developed cardiomyopathy of anemic origin.

Publisher

Healthcare of Tajikistan

Reference15 articles.

1. Vinogradova M.A. Karboksimaltozat zheleza v lechenii anemii v akushersko-ginekologicheskoy praktike [Iron carboxymaltosate in the treatment of anemia in obstetric and gynecological practice]. Klinicheskaya farmakologiya i terapiya - Clinical pharmacology and therapy, 2014, No. 23 (4), pp. 36-44.

2. Vyalov S.S. Effektivnost i bezopasnost liposomalnogo zheleza v lechenii anemii posle rezektsii zheludka ili kishechnika [Efficacy and safety of liposomal iron in the treatment of anemia after gastric or intestinal resection]. Klinicheskaya farmakologiya i terapiya -Clinical pharmacology and therapy, 2016, Vol. 25, No. 4, pp. 42-46.

3. Grzhibovskiy A.M. Opisatelnaya statistika s ispolzovaniem paketov statisticheskikh programm STATISTICA i SPSS [Descriptive statistics using STATISTICA and SPSS statistical program packages]. Nauka i zdravookhranenie - Science and health, 2016. No. 1, pp. 7–23.

4. Zakhidova K.Kh., Kuliev F.A. Anemiya pri khronicheskoy serdechnoy nedostatochnosti: nereshennye problemy lecheniya [Anemia in chronic heart failure: unresolved treatment issues]. Mir meditsiny i biologii - World of medicine and biology, 2013, Vol. 9, No 3 (part 1), pp. 107-112.

5. Zakhidova K.Kh. Vybor optimalnoy terapii pri korrektsii anemicheskogo sindroma u bolnykh s khronicheskoy serdechnoy nedostatochnostyu [Selection of optimal therapy in correction of anemic syndrome in patients with chronic heart failure]. Kardiologiya Cardiology, 2018, Vol. 58, No. 1, pp. 25-31.