Pharmacological inhibition of the transcription factor PU.1 in leukemia
Author:
Funder
Leukemia & Lymphoma Society
Henry and Marilyn Taub Foundation
National Institutes of Health
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://www.jci.org/articles/view/92504/files/pdf
Reference57 articles.
1. Facts 2014-2015. Leukemia & Lymphoma Society. https://www.lls.org/sites/default/files/file_assets/facts.pdf Accessed September 28, 2017
2. Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
3. Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations
4. The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia
5. ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression
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