The small intestine epithelium exempts Foxp3+ Tregs from their IL-2 requirement for homeostasis and effector function

Author:

Prakhar Praveen,Alvarez-DelValle Jaylene,Keller HilaryORCID,Crossman AssiatuORCID,Tai Xuguang,Park Yoo Kyoung,Park Jung-HyunORCID

Funder

National Cancer Institute

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Reference51 articles.

1. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2. Treg cells, life history, and diversity;Benoist;Cold Spring Harb Perspect Biol,2012

3. Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?

4. The Biology of Interleukin-2

5. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol,1995

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