LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling-Reference-Cited by-同舟云学术

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LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling

Published:2020-06-04 Issue:11 Volume:5 Page:
ISSN:2379-3708
Container-title:JCI Insight
language:en
Short-container-title:

Author:

Mancini Alessandra^ORCID,Howard Sasha R.^ORCID,Marelli Federica,Cabrera Claudia P.^ORCID,Barnes Michael R.,Sternberg Michael J.E.,Leprovots Morgane^ORCID,Hadjidemetriou Irene,Monti Elena,David Alessia^ORCID,Wehkalampi Karoliina,Oleari Roberto^ORCID,Lettieri Antonella^ORCID,Vezzoli Valeria,Vassart Gilbert,Cariboni Anna,Bonomi Marco^ORCID,Garcia Marie Isabelle,Guasti Leonardo^ORCID,Dunkel Leo

Funder

National Institute for Health Research

Academy of Medical Sciences

Rosetrees Trust

IRCCS Istituto Auxologico Italiano

Italian Ministry of Health

Biotechnology and Biological Sciences Research Council

Wellcome Trust

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Link

https://insight.jci.org/articles/view/133434/files/pdf

Reference49 articles.

1. IGSF 10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty

2. HS6ST1 Insufficiency Causes Self-Limited Delayed Puberty in Contrast With Other GnRH Deficiency Genes

3. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

4. Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

5. LGR4 and LGR5 are R‐spondin receptors mediating Wnt/β‐catenin and Wnt/PCP signalling

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